RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/8769649http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8769649http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8769649http://www.w3.org/2000/01/rdf-schema#comment"The KRAB repression domain is one of the most widely distributed transcriptional effector domains yet identified, but its mechanism of repression is unknown. We have cloned a corepressor, KAP-1, which associates with the KRAB domain but not with KRAB mutants that have lost repression activity. KAP-1 can enhance KRAB-mediated repression and is a repressor when directly tethered to DNA. KAP-1 contains a RING finger, B boxes, and a PHD finger; the RING-B1-B2 structure is required for KRAB binding and corepression. We propose that KAP-1 may be a universal corepressor for the large family of KRAB domain-containing transcription factors."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.org/dc/terms/identifier"doi:10.1101/gad.10.16.2067"xsd:string
http://purl.uniprot.org/citations/8769649http://purl.org/dc/terms/identifier"doi:10.1101/gad.10.16.2067"xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Speicher D.W."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Speicher D.W."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Friedman J.R."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Friedman J.R."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Fredericks W.J."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Fredericks W.J."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Rauscher F.J. III"xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Rauscher F.J. III"xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Jensen D.E."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Jensen D.E."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Neilson E.G."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Neilson E.G."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Huang X.-P."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/author"Huang X.-P."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/pages"2067-2078"xsd:string
http://purl.uniprot.org/citations/8769649http://purl.uniprot.org/core/pages"2067-2078"xsd:string