| http://purl.uniprot.org/citations/8784257 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8784257 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8784257 | http://www.w3.org/2000/01/rdf-schema#comment | "Vasoactive intestinal peptide (VIP), a neuropeptide present in the lymphoid microenvironment, modulates cytokine expression and affects T cell proliferation. Recent molecular studies identified two VIP receptors. VIP-R1 and VIP-R2, primarily in nonlymphoid cells. In this study, we investigate the expression of VIP-R1 and VIP-R2 mRNA in unstimulated and stimulated lymphocytes and thymocytes, and in various lymphocyte subpopulations. In contrast to VIP-R1 which is constitutively expressed, the expression of VIP-R2 is induced only following stimulation through the TCR-associated CD3 complex. Both CD4+ and CD8+ T cells express VIP-R1 and VIP-R2. Two T cell lines, EL-4.IL-2 and D10.G4.1 express exclusively VIP-R2. VIP induces the expression of the VIP-R2 gene in the absence of additional stimuli. Differential expression and regulation of the two VIP receptors in T lymphocytes suggests different physiological roles in mediating the immunomodulatory activities of VIP and related neuropeptides."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.org/dc/terms/identifier | "doi:10.1016/0165-5728(96)00063-x"xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.org/dc/terms/identifier | "doi:10.1016/0165-5728(96)00063-x"xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Martinez C."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Martinez C."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Johnson M.C."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Johnson M.C."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Delgado M."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Delgado M."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Ganea D."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Ganea D."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Gomariz R.P."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/author | "Gomariz R.P."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/name | "J. Neuroimmunol."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/name | "J. Neuroimmunol."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/pages | "27-38"xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/pages | "27-38"xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/title | "Differential expression of vasoactive intestinal peptide receptors 1 and 2 (VIP-R1 and VIP-R2) mRNA in murine lymphocytes."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/title | "Differential expression of vasoactive intestinal peptide receptors 1 and 2 (VIP-R1 and VIP-R2) mRNA in murine lymphocytes."xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/volume | "68"xsd:string |
| http://purl.uniprot.org/citations/8784257 | http://purl.uniprot.org/core/volume | "68"xsd:string |