| http://purl.uniprot.org/citations/8790347 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8790347 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8790347 | http://www.w3.org/2000/01/rdf-schema#comment | "(+)-Hydantocidin, a recently discovered natural spironucleoside with potent herbicidal activity, is shown to be a proherbicide that, after phosphorylation at the 5' position, inhibits adenylosuccinate synthetase, an enzyme involved in de novo purine synthesis. The mode of binding of hydantocidin 5'-monophosphate to the target enzyme was analyzed by determining the crystal structure of the enzyme-inhibitor complex at 2.6-A resolution. It was found that adenylosuccinate synthetase binds the phosphorylated compound in the same fashion as it does adenosine 5'-monophosphate, the natural feedback regulator of this enzyme. This work provides the first crystal structure of a herbicide-target complex reported to date."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.93.18.9431"xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.93.18.9431"xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Gruetter M.G."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Gruetter M.G."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Cowan-Jacob S.W."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Cowan-Jacob S.W."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Honzatko R.B."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Honzatko R.B."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Ward E."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Ward E."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Fromm H.J."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Fromm H.J."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Chemla P."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Chemla P."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Fonne-Pfister R."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Fonne-Pfister R."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Girardet M."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Girardet M."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Kreuz K.E."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Kreuz K.E."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Schaer H.-P."xsd:string |
| http://purl.uniprot.org/citations/8790347 | http://purl.uniprot.org/core/author | "Schaer H.-P."xsd:string |