| http://purl.uniprot.org/citations/8790375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8790375 | http://www.w3.org/2000/01/rdf-schema#comment | "The surfactant protein A (SP-A) gene was disrupted by homologous recombination in embryonic stem cells that were used to generate homozygous SP-A-deficient mice. SP-A mRNA and protein were not detectable in the lungs of SP-A(-/-) mice, and perinatal survival of SP-A(-/-) mice was not altered compared with wild-type mice. Lung morphology, surfactant proteins B-D, lung tissue, alveolar phospholipid pool sizes and composition, and lung compliance in SP-A(-/-) mice were unaltered. At the highest concentration tested, surfactant from SP-A(-/-) mice produced the same surface tension as (+/+) mice. At lower concentrations, minimum surface tensions were higher for SP-A(-/-) mice. At the ultrastructural level, type II cell morphology was the same in SP-A(+/+) and (-/-) mice. While alveolar phospholipid pool sizes were unperturbed, tubular myelin figures were decreased in the lungs of SP-A(-/-) mice. A null mutation of the murine SP-A gene interferes with the formation of tubular myelin without detectably altering postnatal survival or pulmonary function."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.93.18.9594"xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Ikegami M."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Wert S.E."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Whitsett J.A."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Stripp B.R."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Korfhagen T.R."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Morris R.E."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Bachurski C.J."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Bruno M.D."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Glasser S.W."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Jobe A.H."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Huelsman K.M."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Iwamoto H.S."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/author | "Ross G.F."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/pages | "9594-9599"xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/title | "Altered surfactant function and structure in SP-A gene targeted mice."xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://purl.uniprot.org/core/volume | "93"xsd:string |
| http://purl.uniprot.org/citations/8790375 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8790375 |
| http://purl.uniprot.org/citations/8790375 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8790375 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVX3-mappedCitation-8790375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8790375 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVY3-mappedCitation-8790375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8790375 |