| http://purl.uniprot.org/citations/8798754 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8798754 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8798754 | http://www.w3.org/2000/01/rdf-schema#comment | "We report a novel human gene whose product specifically associates with the negative regulatory domain of the Wilms' tumor gene product (WT1) in a yeast two-hybrid screen and with WT1 in immunoprecipitation and glutathione S-transferase (GST) capture assays. The gene encodes a 17-kDa protein that has 56% amino acid sequence identity with yeast ubiquitin-conjugating enzyme (yUBC) 9, a protein required for cell cycle progression in yeast, and significant identity with other subfamilies of ubiquitin-conjugating enzymes. The human gene fully complements yeast that have a temperature-sensitive yUBC9 gene mutation to fully restore normal growth, indicating that we have cloned a functionally conserved human (h) homolog of yUBC9. Transcripts of hUBC9 of 4.4 kilobases (kb), 2.8 kb, and 1.3 kb were found in all human tissues tested. A single copy of the hUBC9 gene was found and localized to human chromosome 16p13.3. We conclude that hUBC9 retains striking structural and functional conservation with yUBC9 and suggest a possible link of the ubiquitin/proteosome proteolytic pathway and the WT1 transcriptional repressor system."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.271.40.24811"xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.271.40.24811"xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Callen D.F."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Callen D.F."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Qiu Q."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Qiu Q."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Shenk T."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Shenk T."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Testa J.R."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Testa J.R."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Wang Z.-Y."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Wang Z.-Y."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Taguchi T."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Taguchi T."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Seufert W."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Seufert W."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Deuel T.F."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Deuel T.F."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Welsh D."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Welsh D."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Whitmore S.A."xsd:string |
| http://purl.uniprot.org/citations/8798754 | http://purl.uniprot.org/core/author | "Whitmore S.A."xsd:string |