| http://purl.uniprot.org/citations/8804710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8804710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8804710 | http://www.w3.org/2000/01/rdf-schema#comment | "Based on sequence homology with the rat atrial G protein-coupled muscarinic potassium channel (GIRK1 or KGA1/KGB1), a human cDNA encoding a G protein-activated inwardly rectifying K+ channel (HGIRK1) was isolated. The cDNA encodes a protein of 501 amino acids and shares 99% identity to rat GIRK1 in its total amino acid sequence. Southern blot analysis of genomic DNA indicates a high degree of conservation among various species. In the human population a useful NlaIII restriction fragment length polymorphism was found in the coding sequence of HGIRK1. Co-expression of HGIRK1 and the 5-HT1A receptor in Xenopus oocytes resulted in opening of the channel upon treatment with serotonin. HGIRK1 currents showed strong inward rectification and could be blocked by extracellular Ba2+. Northern blot analysis shows that HGIRK1 expression in human is most abundant in the brain, while lower levels are round in kidney and heart."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.org/dc/terms/identifier | "doi:10.1016/0169-328x(95)00349-w"xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.org/dc/terms/identifier | "doi:10.1016/0169-328x(95)00349-w"xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Hampson D.R."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Hampson D.R."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "van Tol H.H.M."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "van Tol H.H.M."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Schoots O."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Schoots O."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Macdonald J.F."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Macdonald J.F."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Dixon L.M."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Dixon L.M."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Nobrega J.N."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Nobrega J.N."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Yue K.T."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/author | "Yue K.T."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/name | "Brain Res. Mol. Brain Res."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/name | "Brain Res. Mol. Brain Res."xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/pages | "23-30"xsd:string |
| http://purl.uniprot.org/citations/8804710 | http://purl.uniprot.org/core/pages | "23-30"xsd:string |