| http://purl.uniprot.org/citations/8808678 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8808678 | http://www.w3.org/2000/01/rdf-schema#comment | "We generated surrogate light chain (SLC)-deficient mice carrying either a V(kappa)J(kappa)-C(kappa) transgene under the control of the kappa promoter and intron enhancer or a V(kappa)J(kappa) gene segment targeted into its physiological position. Efficient rescue of B cell development was seen in the former and partial rescue in the latter. This difference corresponded to a developmentally earlier onset of kappa chain expression from the conventional than from the targeted transgene. Thus, a kappa chain can substitute for SLC in development. However, mechanisms controlling gene expression in addition to gene rearrangements appear to restrict kappa chain expression largely to a cellular compartment into which mu chain-expressing B cell progenitors are selected with the help of the SLC."xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80318-0"xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/author | "Pelanda R."xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/author | "Torres R.M."xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/author | "Rajewsky K."xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/author | "Schaal S."xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/pages | "229-239"xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/title | "A prematurely expressed Ig(kappa) transgene, but not V(kappa)J(kappa) gene segment targeted into the Ig(kappa) locus, can rescue B cell development in lambda5-deficient mice."xsd:string |
| http://purl.uniprot.org/citations/8808678 | http://purl.uniprot.org/core/volume | "5"xsd:string |
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