| http://purl.uniprot.org/citations/8825633 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8825633 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8825633 | http://www.w3.org/2000/01/rdf-schema#comment | "G alpha q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C beta. We report the isolation and characterization of cDNA clones from a frontal cortex cDNA library encoding human G alpha q. The encoded protein is 359 amino acids long and is identical in all but one amino acid residue to mouse G alpha q. Analysis of human genomic DNA reveals an intronless sequence with strong homology to human G alpha q cDNA. In comparison to G alpha q cDNA, this genomic DNA sequence includes several small deletions and insertions that alter the reading frame, multiple single base changes, and a premature termination codon in the open reading frame, hallmarks of a processed pseudogene. Probes derived from human G alpha q cDNA sequence map to both chromosomes 2 and 9 in high-stringency genomic blot analyses of DNA from a panel of human-rodent hybrid cell lines. PCR primers that selectively amplify the pseudogene sequence generate a product only when DNA containing human chromosome 2 is used as the template, indicating that the authentic G alpha q gene (GNAQ) is located on chromosome 9. Regional localization by FISH analysis places GNAQ at 9q21 and the pseudogene at 2q14.3-q21."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1995.1267"xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1995.1267"xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Dong Q."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Dong Q."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "McBride W.O."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "McBride W.O."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Lin K."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Lin K."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Way J."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Way J."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Spiegel A.M."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Spiegel A.M."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Haddad B.R."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Haddad B.R."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Battey J."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Battey J."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Hughes M.R."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Hughes M.R."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Shenker A."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/author | "Shenker A."xsd:string |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/8825633 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |