http://purl.uniprot.org/citations/8849679 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8849679 | http://www.w3.org/2000/01/rdf-schema#comment | "Drosomycin is a 44-residue antifungal peptide with four intramolecular disulfide bridges which have been isolated from immune-challenged Drosophila. To produce adequate amounts of this peptide for 3D-structure analysis, studies on the mode of action and activity spectrum, we expressed a synthetic cDNA in Saccharomyces cerevisiae. For this purpose, we used the mating factor alpha gene and concomitantly overexpressed the KEX2 gene to increase the yield of fully processed drosomycin. Using a combination of Edman degradation and mass spectrometry, we show that drosomycin shares the same array of intramolecular disulfide bridges than plant defensins, in addition to their sequence similarities."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(96)00992-1"xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/author | "Van Dorsselaer A."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/author | "Bulet P."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/author | "Moniatte M."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/author | "Reichhart J.M."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/author | "Fehlbaum P."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/author | "Michaut L."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/pages | "6-10"xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/title | "Determination of the disulfide array of the first inducible antifungal peptide from insects: drosomycin from Drosophila melanogaster."xsd:string |
http://purl.uniprot.org/citations/8849679 | http://purl.uniprot.org/core/volume | "395"xsd:string |
http://purl.uniprot.org/citations/8849679 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8849679 |
http://purl.uniprot.org/citations/8849679 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8849679 |
http://purl.uniprot.org/uniprot/#_P41964-mappedCitation-8849679 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8849679 |
http://purl.uniprot.org/uniprot/P41964 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8849679 |