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http://purl.uniprot.org/citations/8849679http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8849679http://www.w3.org/2000/01/rdf-schema#comment"Drosomycin is a 44-residue antifungal peptide with four intramolecular disulfide bridges which have been isolated from immune-challenged Drosophila. To produce adequate amounts of this peptide for 3D-structure analysis, studies on the mode of action and activity spectrum, we expressed a synthetic cDNA in Saccharomyces cerevisiae. For this purpose, we used the mating factor alpha gene and concomitantly overexpressed the KEX2 gene to increase the yield of fully processed drosomycin. Using a combination of Edman degradation and mass spectrometry, we show that drosomycin shares the same array of intramolecular disulfide bridges than plant defensins, in addition to their sequence similarities."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(96)00992-1"xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/author"Van Dorsselaer A."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/author"Bulet P."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/author"Moniatte M."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/author"Reichhart J.M."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/author"Fehlbaum P."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/author"Michaut L."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/pages"6-10"xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/title"Determination of the disulfide array of the first inducible antifungal peptide from insects: drosomycin from Drosophila melanogaster."xsd:string
http://purl.uniprot.org/citations/8849679http://purl.uniprot.org/core/volume"395"xsd:string
http://purl.uniprot.org/citations/8849679http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8849679
http://purl.uniprot.org/citations/8849679http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8849679
http://purl.uniprot.org/uniprot/#_P41964-mappedCitation-8849679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8849679
http://purl.uniprot.org/uniprot/P41964http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/8849679