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http://purl.uniprot.org/citations/8855272http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8855272http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8855272http://www.w3.org/2000/01/rdf-schema#comment"The vertebrate Dlx gene family consists of homeobox-containing transcription factors distributed in pairs on the same chromosomes as the Hox genes. To investigate the evolutionary history of Dlx genes, we have cloned five new zebrafish family members and have provided additional sequence information for two mouse genes. Phylogenetic analyses of Dlx gene sequences considered in the context of their chromosomal arrangements suggest that an initial tandem duplication produced a linked pair of Dlx genes after the divergence of chordates and arthropods but prior to the divergence of tunicates and vertebrates. This pair of Dlx genes was then duplicated in the chromosomal events that led to the four clusters of Hox genes characteristic of bony fish and tetrapods. It is possible that a pair of Dlx genes linked to the Hoxc cluster has been lost from mammals. We were unable to distinguish between independent duplication and retention of the ancestral state of bony vertebrates to explain the presence of a greater number of Dlx genes in zebrafish than mammals. Determination of the linkage relationship of these additional zebrafish Dlx genes to Hox clusters should help resolve this issue."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.org/dc/terms/identifier"doi:10.1073/pnas.93.20.10858"xsd:string
http://purl.uniprot.org/citations/8855272http://purl.org/dc/terms/identifier"doi:10.1073/pnas.93.20.10858"xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Zhao Z."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Zhao Z."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Ruddle F.H."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Ruddle F.H."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Weiss K.M."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Weiss K.M."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Ekker M."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Ekker M."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Ellies D.L."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Ellies D.L."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Stock D.W."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/author"Stock D.W."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/pages"10858-10863"xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/pages"10858-10863"xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/title"The evolution of the vertebrate Dlx gene family."xsd:string
http://purl.uniprot.org/citations/8855272http://purl.uniprot.org/core/title"The evolution of the vertebrate Dlx gene family."xsd:string