| http://purl.uniprot.org/citations/8858145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8858145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8858145 | http://www.w3.org/2000/01/rdf-schema#comment | "Importin-alpha mediates nuclear protein import by binding nuclear localization signals and importin-beta. We find approximately 30% of SRP1p, the yeast importin-alpha, in a nuclear complex with the Saccharomyces cerevisiae nuclear cap-binding protein complex (CBC). Similarly, a large fraction of Xenopus CBC is associated with importin-alpha in the nucleus. CBC promotes nuclear export of capped U snRNAs and shuttles between nucleus and cytoplasm. The CBC-importin-alpha complex binds specifically to capped RNA, suggesting that CBC might shuttle while bound to importin-alpha. Strikingly, importin-beta binding displaces the RNA from the CBC-importin-alpha complex. Thus, the commitment of CBC for nuclear reentry triggers the release of the export substrate into the cytoplasm. We provide evidence for a mechanism that ensures that importin-mediated RNA release is a specifically cytoplasmic event."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81319-7"xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81319-7"xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Goerlich D."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Goerlich D."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Kostka S."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Kostka S."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Kraft R."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Kraft R."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Hartmann E."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Hartmann E."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Vogel F."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Vogel F."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Mattaj I.W."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Mattaj I.W."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Izaurraide E."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Izaurraide E."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Laskey R.A."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/author | "Laskey R.A."xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/8858145 | http://purl.uniprot.org/core/name | "Cell"xsd:string |