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http://purl.uniprot.org/citations/8878592http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8878592http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8878592http://www.w3.org/2000/01/rdf-schema#comment"The Staphylococcus aureus mutant strain PVI selected in vitro for methicillin resistance overexpressed penicillin-binding protein (PBP) 4. In the wild-type parent strain the pbp4 gene was separated by 419 nucleotides from a divergently transcribed abcA locus coding for an ATP-binding cassette transporter. The mutant PVI was shown to have a deletion in the pbp4-abcA promoter region that affected pbp4 transcription but not expression of abcA. Introduction of the pbp4 gene plus the mutant promoter region into different genetic backgrounds revealed that PBP 4 overproduction was sufficient to increase in vitro-acquired methicillin resistance independently of other chromosomal genes. The role of the AbcA transporter in methicillin resistance remained unknown."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.org/dc/terms/identifier"doi:10.1128/aac.40.9.2121"xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/author"Berger-Bachi B."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/author"Berger-Bachi B."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/author"Henze U.U."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/author"Henze U.U."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/name"Antimicrob. Agents Chemother."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/name"Antimicrob Agents Chemother"xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/pages"2121-2125"xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/pages"2121-2125"xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/title"Penicillin-binding protein 4 overproduction increases beta-lactam resistance in Staphylococcus aureus."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/title"Penicillin-binding protein 4 overproduction increases beta-lactam resistance in Staphylococcus aureus."xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/volume"40"xsd:string
http://purl.uniprot.org/citations/8878592http://purl.uniprot.org/core/volume"40"xsd:string
http://purl.uniprot.org/citations/8878592http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8878592
http://purl.uniprot.org/citations/8878592http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8878592
http://purl.uniprot.org/citations/8878592http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8878592
http://purl.uniprot.org/citations/8878592http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8878592
http://purl.uniprot.org/uniprot/P72354http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/8878592
http://purl.uniprot.org/uniprot/P72355http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/8878592
http://purl.uniprot.org/uniprot/Q57197http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/8878592