http://purl.uniprot.org/citations/8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8879233 | http://www.w3.org/2000/01/rdf-schema#comment | "Thymic selection of natural killer-1+ natural T cells that express alpha beta T cell receptors requires a conserved beta 2-microglobulin-associated molecule, presumably CD1d, displayed by CD4+8+ thymocytes. Here we demonstrate that positive selection of natural T cells occurs independent of transporters associated with antigen presentation-1 (TAP-1) function. Moreover, natural T cells in TAP-1o/o mice are numerically expanded. Several H-2 class Ib molecules function in a TAP-independent manner, suggesting that if expressed in TAP-1o/o thymocytes, they could play a role in natural T cell development. Of these class Ib molecules, H-2TL is expressed by TAP-1o/o thymocytes. Moreover, we find that thymi of TL+ mice congenic or transgenic for H-2T18 also have a numerically expanded natural T cell repertoire compared with TL-mice. This expansion, as in TAP-1o/o thymi, is evident in each of the limited T cell receptor V beta chains expressed by natural T cells, suggesting that TL and CD1d impact similar repertoires. Thus TL, in addition to CD1d, plays a role in natural T cell development."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.184.4.1579"xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Sharma P."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Loh D.Y."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Negishi I."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Joyce S."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Chorney M.J."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Van Kaer L."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "Boesteanu A."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/author | "DeSilva A.D."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/name | "J Exp Med"xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/pages | "1579-1584"xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/title | "Expansion of natural (NK1+) T cells that express alpha beta T cell receptors in transporters associated with antigen presentation-1 null and thymus leukemia antigen positive mice."xsd:string |
http://purl.uniprot.org/citations/8879233 | http://purl.uniprot.org/core/volume | "184"xsd:string |
http://purl.uniprot.org/citations/8879233 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8879233 |
http://purl.uniprot.org/citations/8879233 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8879233 |
http://purl.uniprot.org/uniprot/#_A0A068BER1-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |
http://purl.uniprot.org/uniprot/#_F6QHF1-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |
http://purl.uniprot.org/uniprot/#_Q3U543-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |
http://purl.uniprot.org/uniprot/#_Q62428-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |
http://purl.uniprot.org/uniprot/#_Q62429-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |
http://purl.uniprot.org/uniprot/#_Q64333-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |
http://purl.uniprot.org/uniprot/#_Q3U6V4-mappedCitation-8879233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8879233 |