| http://purl.uniprot.org/citations/8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8919032 | http://www.w3.org/2000/01/rdf-schema#comment | "There is evidence that the cellular responses to cytokines, such as granulocyte colony stimulating factor (G-CSF) and interferons, depend on prior activation of components of the JAK/STAT signalling pathway. We report here that the myeloid cell line NFS-60 shows aberrant JAK/STAT signalling yet elicits expected biological responses to G-CSF and interferons-alpha/beta and gamma. Instead of increased phosphorylation of JAK1 and JAK2 in response to G-CSF and interferon-gamma, and JAK1 and Tyk2 in response to interferon-alpha/beta, we observed only an increase of phosphorylation of Tyk2 in response to all of these cytokines in NFS-60 cells. The subset of STAT proteins being activated in response to these cytokines was unusual as well. G-CSF activated STAT3 and STAT5A, whereas interferons activated, in addition to STAT1 and STAT5 other, as yet unidentified, DNA binding proteins. However, NFS-60 cells show normal biological responses to these cytokines, such as proliferation in response to G-CSF, and reduction of proliferation, induction of an anti-viral response and induction of specific genes in response to interferons."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.org/dc/terms/identifier | "doi:10.3109/08977199609003226"xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/author | "Hamilton J.A."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/author | "Novak U."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/author | "Paradiso L."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/author | "Ward A.C."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/author | "Hertzog P.J."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/name | "Growth Factors"xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/pages | "251-260"xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/title | "Aberrant activation of JAK/STAT pathway components in response to G-CSF, interferon-alpha/beta and interferon-gamma in NFS-60 cells."xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/8919032 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8919032 |
| http://purl.uniprot.org/citations/8919032 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8919032 |
| http://purl.uniprot.org/uniprot/#_P09919-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_O60674-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_P07948-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_P08631-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_P29597-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_P23458-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_P43405-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/#_Q99062-mappedCitation-8919032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/P29597 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8919032 |
| http://purl.uniprot.org/uniprot/P08631 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8919032 |