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http://purl.uniprot.org/citations/8929392http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8929392http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8929392http://www.w3.org/2000/01/rdf-schema#comment"We have cloned and characterized the two remaining unknown genes of the non-oxidative part of the pentose-phosphate pathway of Saccharomyces cerevisiae encoding the enzymes D-ribulose-5-phosphate 3-epimerase (Rpe1p) and D-ribose-5-phosphate ketol-isomerase (Rki1p). Rpe1p has an unexpected high specific activity of 2148 mU x (mg protein)-1 in crude extracts. Deletion mutants of RPE1 show no enzyme activity and are unable to grow on D-xylulose. Unexpectedly, haploid rki1 deletion mutants are not viable. Functional expression of RKI1 was demonstrated following an increase of gene dosage in the haploid rki1 deletion mutant, which restored viability and specific D-ribose-5-phosphate ketol-isomerase activity. Both enzymes show high similarity to the deduced protein sequences of various open reading frames, expressed sequence tags or cDNAs from different organisms."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.org/dc/terms/identifier"doi:10.1007/s002940050149"xsd:string
http://purl.uniprot.org/citations/8929392http://purl.org/dc/terms/identifier"doi:10.1007/s002940050149"xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/author"Miosga T."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/author"Miosga T."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/author"Zimmermann F.K."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/author"Zimmermann F.K."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/name"Curr. Genet."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/name"Curr. Genet."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/pages"404-409"xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/pages"404-409"xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/title"Cloning and characterization of the first two genes of the non-oxidative part of the Saccharomyces cerevisiae pentose-phosphate pathway."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/title"Cloning and characterization of the first two genes of the non-oxidative part of the Saccharomyces cerevisiae pentose-phosphate pathway."xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/volume"30"xsd:string
http://purl.uniprot.org/citations/8929392http://purl.uniprot.org/core/volume"30"xsd:string
http://purl.uniprot.org/citations/8929392http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8929392
http://purl.uniprot.org/citations/8929392http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8929392
http://purl.uniprot.org/citations/8929392http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8929392
http://purl.uniprot.org/citations/8929392http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8929392
http://purl.uniprot.org/uniprot/Q12189http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/8929392
http://purl.uniprot.org/uniprot/P46969http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/8929392