http://purl.uniprot.org/citations/8944023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8944023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8944023 | http://www.w3.org/2000/01/rdf-schema#comment | "The hereditary breast and ovarian cancer gene, BRCA1, encodes a large polypeptide that contains the cysteine-rich RING motif, a zinc-binding domain found in a variety of regulatory proteins. Here we describe a novel protein that interacts in vivo with the N-terminal region of BRCA1. This BRCA1-associated RING domain (BARD1) protein contains an N-terminal RING motif, three tandem ankyrin repeats, and a C-terminal sequence with significant homology to the phylogenetically conserved BRCT domains that lie near the C terminus of BRCA1. The BARD1/BRCA1 interaction is disrupted by BRCA1 missense mutations that segregate with breast cancer susceptibility, indicating that BARD1 may be involved in mediating tumour suppression by BRCA1."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng1296-430"xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng1296-430"xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Baer R."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Baer R."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Wang Z.W."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Wang Z.W."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Bowcock A.M."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Bowcock A.M."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Hwang L.-Y."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Hwang L.-Y."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Phung A."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Phung A."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Spillman M.A."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Spillman M.A."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Tsan J.T."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Tsan J.T."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Wu L.C."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Wu L.C."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Xu X.L."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Xu X.L."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Yang M.-C.W."xsd:string |
http://purl.uniprot.org/citations/8944023 | http://purl.uniprot.org/core/author | "Yang M.-C.W."xsd:string |