| http://purl.uniprot.org/citations/8969220 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8969220 | http://www.w3.org/2000/01/rdf-schema#comment | "The class B, type I scavenger receptor, SR-BI, binds high density lipoprotein (HDL) and can mediate selective uptake of HDL cholesteryl esters by cultured cells. The high levels of expression of SR-BI in steroidogenic tissues and the importance of selective uptake from HDL as a source of cholesterol for steroidogenesis raised the possibility that SR-BI may participate in cholesterol delivery to steroidogenic tissues in vivo. We have used immunoblotting and immunohistochemical methods to show that SR-BI is specifically expressed in a distinctive pattern on the surfaces of steroid-producing cells in the murine adrenal gland's cortex and that its expression in vivo is induced by adrenocorticotropic hormone and suppressed by glucocorticoids. Thus, expression of SR-BI protein is coordinately regulated with adrenal steroidogenesis. These data provide strong support for the hypothesis that SR-BI is a physiologically relevant HDL receptor that provides substrate cholesterol for steroid hormone synthesis."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.271.52.33545"xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Williams D.L."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Rigotti A."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Krieger M."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "DeMattos R.B."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Temel R.E."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Edelman E.R."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Iqbal S.N."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/author | "Seifert P."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/pages | "33545-33549"xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/title | "Regulation by adrenocorticotropic hormone of the in vivo expression of scavenger receptor class B type I (SR-BI), a high density lipoprotein receptor, in steroidogenic cells of the murine adrenal gland."xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://purl.uniprot.org/core/volume | "271"xsd:string |
| http://purl.uniprot.org/citations/8969220 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8969220 |
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