http://purl.uniprot.org/citations/8978042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8978042 | http://www.w3.org/2000/01/rdf-schema#comment | "Sets of sense and antisense P-element constructs controlled by a heat-shock-inducible promoter were tested for their ability to repress manifestations of P-element activity in vivo. As a group, the antisense constructs repressed pupal lethality, a somatic manifestation of P activity, and this repression was significantly enhanced by heat shock. Three of the 11 antisense constructs also repressed gonadal dysgenesis, a manifestation of P activity in the female germ line; however, none had any effect on P-element-mediated mutability in the male germ line. Among the 13 different heat-shock-inducible sense constructs that were tested, those containing the KP and DP elements were strong repressors of pupal lethality, gonadal dysgenesis and P-element-mediated mutability; however, individual lines carrying these constructs varied in their ability to repress each of these traits, presumably because of genomic position effects. With the exception of the sense construct that contained a complete P element, none of the sense or antisense constructs repressed a lacZ reporter gene driven by the P-element promoter. Overall, the experimental results suggest that in nature, P-element activity could be regulated by P-encoded polypeptides and by antisense P RNAs."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/144.4.1529"xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Lund C."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Jordan M."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Simmons M.J."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Grimes C.D."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Raymond J.D."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Belinco C."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Haake B.C."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Ojala T.A."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/author | "Papermaster D."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/pages | "1529-1544"xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/title | "Repression of hybrid dysgenesis in Drosophila melanogaster by heat-shock-inducible sense and antisense P-element constructs."xsd:string |
http://purl.uniprot.org/citations/8978042 | http://purl.uniprot.org/core/volume | "144"xsd:string |
http://purl.uniprot.org/citations/8978042 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8978042 |
http://purl.uniprot.org/citations/8978042 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8978042 |
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http://purl.uniprot.org/uniprot/#_M9PBB5-mappedCitation-8978042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8978042 |
http://purl.uniprot.org/uniprot/#_H5V8A9-mappedCitation-8978042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8978042 |