| http://purl.uniprot.org/citations/9000520 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9000520 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9000520 | http://www.w3.org/2000/01/rdf-schema#comment | "The nucleotide sequences of the dnaQ genes from Salmonella typhimurium and Buchnera aphidicola, encoding the epsilon-subunit of the DNA polymerase III holoenzyme, have been determined. The Salmonella typhimurium dnaQ protein consists of 243 amino acid residues with a calculated molecular weight of 27224. The Buchnera aphidicola dnaQ protein contains 233 amino acid residues with a calculated molecular weight of 27170. A multiple sequence alignment of the amino acid sequences of the dnaQ proteins and those of DNA polymerase IIIs from Gram-positive bacteria produced six homologous segments. These homologous segments contain highly conserved amino acid sequence motifs involved in catalytically important metal ion bindings (ligands 1, 2 and 3). However, metal ligand 4 is found to be altered in the 3'-5' exonuclease domain of the family C DNA polymerases and dnaQ proteins in Gram-negative bacteria. From these results, we propose that the last common ancestor of the dnaQ gene of Gram-negative bacteria and the DNA polymerase III gene (pol C gene) of Gram-positive bacteria was a single gene containing both 3'-5' exonuclease and DNA polymerase domains and then the dnaQ gene separated from the polymerase gene in Gram-negative bacteria."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(96)01361-0"xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(96)01361-0"xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/author | "Ito J."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/author | "Ito J."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/author | "Braithwaite D.K."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/author | "Braithwaite D.K."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/pages | "94-98"xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/pages | "94-98"xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/title | "Evolution of dnaQ, the gene encoding the editing 3' to 5' exonuclease subunit of DNA polymerase III holoenzyme in Gram-negative bacteria."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/title | "Evolution of dnaQ, the gene encoding the editing 3' to 5' exonuclease subunit of DNA polymerase III holoenzyme in Gram-negative bacteria."xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/volume | "400"xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://purl.uniprot.org/core/volume | "400"xsd:string |
| http://purl.uniprot.org/citations/9000520 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9000520 |
| http://purl.uniprot.org/citations/9000520 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9000520 |
| http://purl.uniprot.org/citations/9000520 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9000520 |
| http://purl.uniprot.org/citations/9000520 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9000520 |