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http://purl.uniprot.org/citations/9019411http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9019411http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9019411http://www.w3.org/2000/01/rdf-schema#comment"We have found that the mammalian Ran GTPase-activating protein RanGAP1 is highly concentrated at the cytoplasmic periphery of the nuclear pore complex (NPC), where it associates with the 358-kDa Ran-GTP-binding protein RanBP2. This interaction requires the ATP-dependent posttranslational conjugation of RanGAP1 with SUMO-1 (for small ubiquitin-related modifier), a novel protein of 101 amino acids that contains low but significant homology to ubiquitin. SUMO-1 appears to represent the prototype for a novel family of ubiquitin-related protein modifiers. Inhibition of nuclear protein import resulting from antibodies directed at NPC-associated RanGAP1 cannot be overcome by soluble cytosolic RanGAP1, indicating that GTP hydrolysis by Ran at RanBP2 is required for nuclear protein import."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)81862-0"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)81862-0"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Gerace L."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Gerace L."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Guan T."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Guan T."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Delphin C."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Delphin C."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Melchior F."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Melchior F."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Mahajan R."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/author"Mahajan R."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/pages"97-107"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/pages"97-107"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/title"A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/title"A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2."xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/volume"88"xsd:string
http://purl.uniprot.org/citations/9019411http://purl.uniprot.org/core/volume"88"xsd:string