| http://purl.uniprot.org/citations/9032445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9032445 | http://www.w3.org/2000/01/rdf-schema#comment | "Simultaneous multiple alignment of available sequences of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase revealed several segments of conserved residues in the 2-kinase domain. The sequence of the kinase domain was also compared with proteins of known three-dimensional structure. No similarity was found between the kinase domain of 6-phosphofructo-2-kinase and 6-phosphofructo-1-kinase. This questions the modelling of the 2-kinase domain on bacterial 6-phosphofructo-1-kinase that has previously been proposed [Bazan, Fletterick and Pilkis (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 9642-9646]. However, sequence similarities were found between the 2-kinase domain and several nucleotide-binding proteins, the most similar being adenylate kinase. A structural model of the 2-kinase domain based on adenylate kinase is proposed. It accommodates all the results of site-directed mutagenesis studies carried out to date on residues in the 2-kinase domain. It also allows residues potentially involved in catalysis and/or substrate binding to be predicted."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.org/dc/terms/identifier | "doi:10.1042/bj3210615"xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/author | "Rider M.H."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/author | "Vertommen D."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/author | "Bertrand L."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/author | "Hue L."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/author | "Depiereux E."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/author | "Feytmans E."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/name | "Biochem J"xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/pages | "615-621"xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/title | "Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase."xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://purl.uniprot.org/core/volume | "321"xsd:string |
| http://purl.uniprot.org/citations/9032445 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9032445 |
| http://purl.uniprot.org/citations/9032445 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9032445 |
| http://purl.uniprot.org/uniprot/#_P32604-mappedCitation-9032445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9032445 |
| http://purl.uniprot.org/uniprot/P32604 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9032445 |