| http://purl.uniprot.org/citations/9038372 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9038372 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9038372 | http://www.w3.org/2000/01/rdf-schema#comment | "STE20-homologous proteins have been implicated in mammalian MAP kinase pathways as important transducers of signals from p21 family GTPases. We have cloned a novel STE20 family member, which we call KHS for kinase homologous to SPS1/STE20, that encodes a kinase of 95 kD which is expressed in a variety of tissues. Transiently expressed fusion protein GST-KHS exhibits phosphotransferase activity toward a panel of test substrates, including myelin basic protein (MBP), which is phosphorylated by all known STE20 homologues. KHS is most closely related to another human STE20, GC kinase (74% similar in the catalytic domain), which has recently been placed upstream of the stress-activated MAP kinases (SAPKs/JNKs). KHS also activates JNK in transient coexpression experiments, suggesting a role for KHS in the stress response of fibroblasts. Characterization and comparison of the regulation of these two kinases will be important in elucidating MAP kinase signalling cascades."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1200877"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1200877"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/author | "Blenis J."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/author | "Blenis J."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/author | "Tung R.M."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/author | "Tung R.M."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/pages | "653-659"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/pages | "653-659"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/title | "A novel human SPS1/STE20 homologue, KHS, activates jun N-terminal kinase."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/title | "A novel human SPS1/STE20 homologue, KHS, activates jun N-terminal kinase."xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/9038372 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9038372 |
| http://purl.uniprot.org/citations/9038372 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9038372 |
| http://purl.uniprot.org/citations/9038372 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9038372 |
| http://purl.uniprot.org/citations/9038372 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9038372 |
| http://purl.uniprot.org/uniprot/Q9Y4K4 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9038372 |
| http://purl.uniprot.org/embl-cds/AAB48435.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9038372 |