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http://purl.uniprot.org/citations/9047378http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9047378http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9047378http://www.w3.org/2000/01/rdf-schema#comment"The conserved lymphokine elements-0 (CLE0) in the IL5 promoter is essential for the expression of IL-5. Here, we report the cloning and expression of a cDNA encoding a novel CLE0-binding protein, CLEBP-1 from a mouse Th2 clone, D10.G4.1. Interestingly, it was found that the CLEBP1 cDNA sequence was almost identical to the sequences of known high mobility group-1 (HMG1) cDNAs. When expressed as a recombinant fusion protein in Escherichia coli, CLEBP-1 was shown to bind to the IL5-CLE0 element in electrophoretic mobility-shift assays (EMSA) and southwestern blot analysis. The CLEBP-1 fusion protein cross-reacts with and-HMG-1/2 in Western blot analysis. It also binds to the CLE0 elements of IL4, GMCSF and GCSF genes. CLEBP-1 and closely related HMG-1 and HMG-2 proteins may play key roles in facilitating the expression of the lymphokine genes that contain CLE0 elements."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.org/dc/terms/identifier"doi:10.1016/s0161-5890(96)00073-9"xsd:string
http://purl.uniprot.org/citations/9047378http://purl.org/dc/terms/identifier"doi:10.1016/s0161-5890(96)00073-9"xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/author"Ghosh B."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/author"Ghosh B."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/author"Marsh D.G."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/author"Marsh D.G."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/author"Marrugo J."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/author"Marrugo J."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/name"Mol. Immunol."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/name"Mol. Immunol."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/pages"1119-1125"xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/pages"1119-1125"xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/title"The conserved lymphokine element-0 in the IL5 promoter binds to a high mobility group-1 protein."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/title"The conserved lymphokine element-0 in the IL5 promoter binds to a high mobility group-1 protein."xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/volume"33"xsd:string
http://purl.uniprot.org/citations/9047378http://purl.uniprot.org/core/volume"33"xsd:string
http://purl.uniprot.org/citations/9047378http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9047378
http://purl.uniprot.org/citations/9047378http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9047378
http://purl.uniprot.org/citations/9047378http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9047378
http://purl.uniprot.org/citations/9047378http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9047378