http://purl.uniprot.org/citations/9055081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9055081 | http://www.w3.org/2000/01/rdf-schema#comment | "Caenorhabditis elegans uses chemosensation to determine its course of development. Young larvae can arrest as dauer larvae in response to increasing population density, which they measure by a nematodeexcreted pheromone, and decreasing food supply. Dauer larvae can resume development in response to a decrease in pheromone and increase in food concentration. We show here that two novel G protein alpha subunits (GPA-2 and GPA-3) show promoter activity in subsets of chemosensory neurons and are involved in the decision to form dauer larvae primarily through the response to dauer pheromone. Dominant activating mutations in these G proteins result in constitutive, pheromone-independent dauer formation, whereas inactivation results in reduced sensitivity to pheromone, and, under certain conditions, an alteration in the response to food. Interactions between gpa-2, gpa-3 and other genes controlling dauer formation suggest that these G proteins may act in parallel to regulate the neuronal decision making that precedes dauer formation."xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/145.3.715"xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/author | "Plasterk R.H."xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/author | "Sternberg P.W."xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/author | "Mendel J.E."xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/author | "Zwaal R.R."xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/pages | "715-727"xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/title | "Two neuronal G proteins are involved in chemosensation of the Caenorhabditis elegans Dauer-inducing pheromone."xsd:string |
http://purl.uniprot.org/citations/9055081 | http://purl.uniprot.org/core/volume | "145"xsd:string |
http://purl.uniprot.org/citations/9055081 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9055081 |
http://purl.uniprot.org/citations/9055081 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9055081 |
http://purl.uniprot.org/uniprot/P28052#attribution-4464FC49BE9689ED1D0AAE54846E837F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9055081 |
http://purl.uniprot.org/uniprot/#_P28052-mappedCitation-9055081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9055081 |
http://purl.uniprot.org/uniprot/#_P22454-mappedCitation-9055081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9055081 |
http://purl.uniprot.org/uniprot/P28052 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9055081 |
http://purl.uniprot.org/uniprot/P22454 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9055081 |