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http://purl.uniprot.org/citations/9076678http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9076678http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9076678http://www.w3.org/2000/01/rdf-schema#comment"We have cloned a mouse cDNA encoding a Mothers-against-dpp (MAD)-related protein, MADR1. Madr1 is ubiquitously expressed in the mouse embryo, indicating a broad function in a variety of tissue during embryogenesis, potentially relaying signals of numerous BMPs. However, its expression in the testis is strictly germ cell-specific and developmentally regulated. Testicular Madr1 expression starts in some seminiferous tubules at 2 weeks of age. After mid-puberty, a stage-specific Madr1 expression is established. During the cycling of the seminiferous epithelium, Madr1 expression initiates in the pachytene spermatocytes of stage V seminiferous tubules, peaks at stage X, then decreases as pachytene spermatocytes differentiate into secondary spermatocytes and then round spermatids. In the testis of adult Bmp8b homozygous mutant males, the Madr1-expressing pachytene spermatocytes are the first cell population to show increased apoptosis. These data suggest that MADR1 serves as a downstream component of the BMP8 signaling pathway during the differentiation of meiotic male germ cells."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.org/dc/terms/identifier"doi:10.1016/s0925-4773(96)00622-3"xsd:string
http://purl.uniprot.org/citations/9076678http://purl.org/dc/terms/identifier"doi:10.1016/s0925-4773(96)00622-3"xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/author"Zhao G.-Q."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/author"Zhao G.-Q."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/author"Hogan B.L.M."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/author"Hogan B.L.M."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/name"Mech. Dev."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/name"Mech. Dev."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/pages"63-73"xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/pages"63-73"xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/title"Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/title"Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse."xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/volume"61"xsd:string
http://purl.uniprot.org/citations/9076678http://purl.uniprot.org/core/volume"61"xsd:string
http://purl.uniprot.org/citations/9076678http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9076678
http://purl.uniprot.org/citations/9076678http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9076678
http://purl.uniprot.org/citations/9076678http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9076678
http://purl.uniprot.org/citations/9076678http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9076678
http://purl.uniprot.org/embl-cds/AAB18256.1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9076678
http://purl.uniprot.org/uniprot/P70340http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9076678