| http://purl.uniprot.org/citations/9108020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9108020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9108020 | http://www.w3.org/2000/01/rdf-schema#comment | "OspA (outer surface protein A) is an abundant immunogenic lipoprotein of the Lyme disease spirochete Borrelia burgdorferi. The crystal structure of a soluble recombinant form of OspA was solved in a complex with the Fab fragment of mouse monoclonal antibody 184.1 and refined to a resolution of 1.9 A. OspA has a repetitive antiparallel beta topology with an unusual nonglobular region of "freestanding" sheet connecting globular N- and C-terminal domains. Arrays of residues with alternating charges are a predominant feature of the folding pattern in the nonglobular region. The 184.1 epitope overlaps with a well conserved surface in the N-terminal domain, and a hydrophobic cavity buried in a positively charged cleft in the C-terminal domain is a potential binding site for an unknown ligand. An exposed variable region on the C-terminal domain of OspA is predicted to be an important factor in the worldwide effectiveness of OspA-based vaccines."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.8.3584"xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.8.3584"xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Dunn J.J."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Dunn J.J."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Li H."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Li H."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Luft B.J."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Luft B.J."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Lawson C.L."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/author | "Lawson C.L."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/pages | "3584-3589"xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/pages | "3584-3589"xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/title | "Crystal structure of Lyme disease antigen outer surface protein A complexed with an Fab."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/title | "Crystal structure of Lyme disease antigen outer surface protein A complexed with an Fab."xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/volume | "94"xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://purl.uniprot.org/core/volume | "94"xsd:string |
| http://purl.uniprot.org/citations/9108020 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9108020 |
| http://purl.uniprot.org/citations/9108020 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9108020 |