| http://purl.uniprot.org/citations/9108131 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9108131 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9108131 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/9108131 | http://www.w3.org/2000/01/rdf-schema#comment | "gamma-Linolenic acid (GLA; C18:3 delta(6,9,12)) is a component of the seed oils of evening primrose (Oenothera spp.), borage (Borago officinalis L.), and some other plants. It is widely used as a dietary supplement and for treatment of various medical conditions. GLA is synthesized by a delta6-fatty acid desaturase using linoleic acid (C18:2 delta(9,12)) as a substrate. To enable the production of GLA in conventional oilseeds, we have isolated a cDNA encoding the delta6-fatty acid desaturase from developing seeds of borage and confirmed its function by expression in transgenic tobacco plants. Analysis of leaf lipids from a transformed plant demonstrated the accumulation of GLA and octadecatetraenoic acid (C18:4 delta(6,9,12,15)) to levels of 13.2% and 9.6% of the total fatty acids, respectively. The borage delta6-fatty acid desaturase differs from other desaturase enzymes, characterized from higher plants previously, by the presence of an N-terminal domain related to cytochrome b5."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.8.4211"xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.8.4211"xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Shewry P.R."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Shewry P.R."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Napier J.A."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Napier J.A."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Sayanova O."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Sayanova O."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Smith M.A."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Smith M.A."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Christie W.W."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Christie W.W."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Dobson G."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Dobson G."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Lapinskas P.A."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Lapinskas P.A."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Stobart K."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/author | "Stobart K."xsd:string |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9108131 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |