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http://purl.uniprot.org/citations/9111339http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9111339http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9111339http://www.w3.org/2000/01/rdf-schema#comment"The Saccharomyces cerevisiae RIM15 gene was identified previously through a mutation that caused reduced ability to undergo meiosis. We report here an analysis of the cloned RIM15 gene, which specifies a 1,770-residue polypeptide with homology to serine/threonine protein kinases. Rim15p is most closely related to Schizosaccharomyces pombe cek1+. Analysis of epitope-tagged derivatives indicates that Rim15p has autophosphorylation activity. Deletion of RIM15 causes reduced expression of several early meiotic genes (IME2, SPO13, and HOP1) and of IME1, which specifies an activator of early meiotic genes. However, overexpression of IME1 does not permit full expression of early meiotic genes in a rim15delta mutant. Ime1p activates early meiotic genes through its interaction with Ume6p, and analysis of Rim15p-dependent regulatory sites at the IME2 promoter indicates that activation through Ume6p is defective. Two-hybrid interaction assays suggest that Ime1p-Ume6p interaction is diminished in a rim15 mutant. Glucose inhibits Ime1p-Ume6p interaction, and we find that Rim15p accumulation is repressed in glucose-grown cells. Thus, glucose repression of Rim15p may be responsible for glucose inhibition of Ime1p-Ume6p interaction."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.org/dc/terms/identifier"doi:10.1128/mcb.17.5.2688"xsd:string
http://purl.uniprot.org/citations/9111339http://purl.org/dc/terms/identifier"doi:10.1128/mcb.17.5.2688"xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/author"Mitchell A.P."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/author"Mitchell A.P."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/author"Vidan S."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/author"Vidan S."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/pages"2688-2697"xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/pages"2688-2697"xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/title"Stimulation of yeast meiotic gene expression by the glucose-repressible protein kinase Rim15p."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/title"Stimulation of yeast meiotic gene expression by the glucose-repressible protein kinase Rim15p."xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/9111339http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/9111339http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9111339
http://purl.uniprot.org/citations/9111339http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9111339
http://purl.uniprot.org/citations/9111339http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9111339
http://purl.uniprot.org/citations/9111339http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9111339
http://purl.uniprot.org/uniprot/P43565http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9111339
http://purl.uniprot.org/uniprot/P43565#attribution-B62D5D821EC6350E2DBA4BB8964C6FD6http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/9111339