| http://purl.uniprot.org/citations/9118959 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9118959 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9118959 | http://www.w3.org/2000/01/rdf-schema#comment | "Receptor protein tyrosine phosphatase beta (RPTPbeta) expressed on the surface of glial cells binds to the glycosylphosphatidylinositol (GPI)-anchored recognition molecule contactin on neuronal cells leading to neurite outgrowth. We describe the cloning of a novel contactin-associated transmembrane receptor (p190/Caspr) containing a mosaic of domains implicated in protein-protein interactions. The extracellular domain of Caspr contains a neurophilin/coagulation factor homology domain, a region related to fibrinogen beta/gamma, epidermal growth factor-like repeats, neurexin motifs as well as unique PGY repeats found in a molluscan adhesive protein. The cytoplasmic domain of Caspr contains a proline-rich sequence capable of binding to a subclass of SH3 domains of signaling molecules. Caspr and contactin exist as a complex in rat brain and are bound to each other by means of lateral (cis) interactions in the plasma membrane. We propose that Caspr may function as a signaling component of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. The binding of RPTPbeta to the contactin-Caspr complex could provide a mechanism for cell-cell communication between glial cells and neurons during development."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/16.5.978"xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/16.5.978"xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Martinez R."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Martinez R."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Peles E."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Peles E."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Schilling J."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Schilling J."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Schlessinger J."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Schlessinger J."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Plowman G.D."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Plowman G.D."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Grumet M."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Grumet M."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Lustig M."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Lustig M."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Nativ M."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/author | "Nativ M."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/9118959 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |