http://purl.uniprot.org/citations/9126489 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9126489 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9126489 | http://www.w3.org/2000/01/rdf-schema#comment | "Class IV alcohol dehydrogenase (ADH) has been shown to function in vitro as a retinol dehydrogenase catalyzing the synthesis of retinoic acid, a pleiotropic gene regulator. To enable genetic studies on the function of this enzyme and regulation of its gene, we have screened a genomic library and isolated the mouse class IV ADH gene (Adh3). The complete mouse class IV ADH coding region was found in nine exons spanning a 14-kb region. Primer extension analysis was used to map the transcription initiation site to a position lying 30 bp upstream of the ATG translation start codon. Nucleotide sequence analysis of the promoter region indicated an absence of both TATA-box and GC-box sequences; this distinguishes it from the promoters for class I, II, and III ADH genes. Sequence comparison of the mouse and human class IV ADH promoters indicated that they share a conserved region located 125-145 bp upstream of the coding region containing adjacent sequences matching the consensus binding sites for transcription factors AP-1 and C/EBP."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1997.4637"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1997.4637"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Duester G."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Duester G."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Foglio M.H."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Foglio M.H."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Zgombic-Knight M."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Zgombic-Knight M."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Deltour L."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Deltour L."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Haselbeck R.J."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/author | "Haselbeck R.J."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/pages | "105-109"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/pages | "105-109"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/title | "Gene structure and promoter for Adh-3 encoding mouse class IV alcohol dehydrogenase (retinol dehydrogenase)."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/title | "Gene structure and promoter for Adh-3 encoding mouse class IV alcohol dehydrogenase (retinol dehydrogenase)."xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/volume | "41"xsd:string |
http://purl.uniprot.org/citations/9126489 | http://purl.uniprot.org/core/volume | "41"xsd:string |