| http://purl.uniprot.org/citations/9168999 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9168999 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9168999 | http://www.w3.org/2000/01/rdf-schema#comment | "SNARE proteins have been implicated in the insulin-induced translocation of vesicles containing the GLUT4 glucose transporter to the plasma membrane of adipocytes. The role of the target SNARE SNAP-25 or its homologs in this process was investigated by screening a mouse adipocyte cDNA library with rat SNAP-25 and human SNAP-23 cDNA probes. Both positive clones isolated encoded a protein with 87% sequence identity to human SNAP-23, and which was therefore designated mouse SNAP-23. Immunoblot and immunofluorescence analyses revealed that SNAP-23 is located predominantly in the plasma membrane of 3T3-L1 adipocytes incubated in the absence or presence of insulin. Of syntaxins 1 to 5, SNAP-23 bound with the highest affinity to syntaxins 1 and 4 in the yeast two-hybrid system. Expression of SNAP-23, syntaxin 4, and the syntaxin-binding protein Munc 18c in COS cells revealed that Munc18c reduced the amount of SNAP-23 bound to syntaxin 4 in a concentration-dependent manner. These results suggest that the binding of SNAP-23 to syntaxin 4 is inhibited by Munc18c in adipocytes."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.6560"xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.6560"xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Araki S."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Araki S."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Kasuga M."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Kasuga M."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Mori H."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Mori H."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Kubota T."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Kubota T."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Shinoda H."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Shinoda H."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Niki T."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Niki T."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Okazawa H."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Okazawa H."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Tamori Y."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Tamori Y."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Kawanishi M."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Kawanishi M."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Masugi J."xsd:string |
| http://purl.uniprot.org/citations/9168999 | http://purl.uniprot.org/core/author | "Masugi J."xsd:string |