http://purl.uniprot.org/citations/9175835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9175835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9175835 | http://www.w3.org/2000/01/rdf-schema#comment | "Tip of herpesvirus saimiri associates with Lck and down-regulates Lck-mediated activation. We identified a novel cellular Tip-associated protein (Tap) by a yeast two-hybrid screen. Tap associated with Tip following transient expression in COS-1 cells and stable expression in human Jurkat-T cells. Expression of Tip and Tap in Jurkat-T cells induced dramatic cell aggregation. Aggregation was likely caused by the up-regulated surface expression of adhesion molecules including integrin alpha, L-selectin, ICAM-3, and H-CAM. Furthermore, NF-kappaB transcriptional factor of aggregated cells had approximately 40-fold higher activity than that of parental cells. Thus, Tap is likely to be an important cellular mediator of Tip function in T cell transformation by herpesvirus saimiri."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80345-3"xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80345-3"xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Lee H."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Lee H."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Jung J.U."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Jung J.U."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "DeMaria M."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "DeMaria M."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Rosenzweig M."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Rosenzweig M."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Seol W."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Seol W."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Yoon D.-W."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/author | "Yoon D.-W."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/pages | "571-582"xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/pages | "571-582"xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/title | "Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation."xsd:string |
http://purl.uniprot.org/citations/9175835 | http://purl.uniprot.org/core/title | "Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation."xsd:string |