| http://purl.uniprot.org/citations/9182526 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9182526 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9182526 | http://www.w3.org/2000/01/rdf-schema#comment | "Recent studies have described a widely expressed adaptor-like complex, named AP-3, which is likely involved in protein sorting in exocytic/endocytic pathways. The AP-3 complex is composed of four distinct subunits. Here, we report the identification of one of the subunits of this complex, which we call beta3A-adaptin. The predicted amino acid sequence of beta3A-adaptin reveals that the protein is closely related to the neuron-specific protein beta-NAP (61% overall identity) and more distantly related to the beta1- and beta2-adaptin subunits of the clathrin-associated adaptor complexes AP-1 and AP-2, respectively. Sequence comparisons also suggest that beta3A-adaptin has a domain organization similar to beta-NAP and to beta1- and beta2-adaptins. beta3A-adaptin is expressed in all tissues and cells examined. Co-purification and co-precipitation analyses demonstrate that beta3A-adaptin corresponds to the approximately 140-kDa subunit of the ubiquitous AP-3 complex, the other subunits being delta-adaptin, p47A (now called mu3A) and sigma3 (A or B). beta3A-adaptin is phosphorylated on serine residues in vivo while the other subunits of the complex are not detectably phosphorylated. beta3A-adaptin is not present in significant amounts in clathrin-coated vesicles. The characteristics of beta3A-adaptin reported here lend support to the idea that AP-3 is a structural and functional homolog of the clathrin-associated adaptors AP-1 and AP-2."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.272.24.15078"xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.272.24.15078"xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/author | "Bonifacino J.S."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/author | "Bonifacino J.S."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/author | "Dell'Angelica E.C."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/author | "Dell'Angelica E.C."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/author | "Ooi C.E."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/author | "Ooi C.E."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/pages | "15078-15084"xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/pages | "15078-15084"xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/title | "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/title | "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3."xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/volume | "272"xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://purl.uniprot.org/core/volume | "272"xsd:string |
| http://purl.uniprot.org/citations/9182526 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9182526 |
| http://purl.uniprot.org/citations/9182526 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9182526 |
| http://purl.uniprot.org/citations/9182526 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9182526 |
| http://purl.uniprot.org/citations/9182526 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9182526 |