http://purl.uniprot.org/citations/9212230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9212230 | http://www.w3.org/2000/01/rdf-schema#comment | "We have examined several types of tumor cell lines and shown that they invariably expressed little or no Egr-1, in contrast to their normal counterparts. We have previously shown that the expression of exogenous Egr-1 in human breast and other tumor cells markedly reduces transformed growth and tumorigenicity. We therefore hypothesized that the loss of Egr-1 expression plays a role in transformation. All human and mouse breast cancer cell lines and tumors examined had reduced Egr-1 expression compared with their normal counterparts. Reduced Egr-1 expression was also observed in 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumors, and this level increased to normal levels in tumors that regressed after tamoxifen treatment. We concluded, therefore, that loss of Egr-1 expression may play a role in the deregulation of normal growth in the tumorigenic process and that Egr-1 acts as a tumor suppressor gene."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.org/dc/terms/identifier | "doi:10.1002/(sici)1097-0215(19970703)72:1<102::aid-ijc15>3.0.co;2-l"xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "Fan Y."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "Huang R.P."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "Gottardis M.M."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "Adamson E.D."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "Mercola D."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "Niemeyer C."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/author | "de Belle I."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/name | "Int J Cancer"xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/pages | "102-109"xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/title | "Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation."xsd:string |
http://purl.uniprot.org/citations/9212230 | http://purl.uniprot.org/core/volume | "72"xsd:string |
http://purl.uniprot.org/citations/9212230 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9212230 |
http://purl.uniprot.org/citations/9212230 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9212230 |
http://purl.uniprot.org/uniprot/#_A0A0H2UHR3-mappedCitation-9212230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9212230 |
http://purl.uniprot.org/uniprot/#_P08154-mappedCitation-9212230 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9212230 |
http://purl.uniprot.org/uniprot/A0A0H2UHR3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9212230 |
http://purl.uniprot.org/uniprot/P08154 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9212230 |