| http://purl.uniprot.org/citations/9214619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9214619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9214619 | http://www.w3.org/2000/01/rdf-schema#comment | "Intracellular vesicular traffic is controlled in part by v- and t-SNAREs, integral membrane proteins which allow specific interaction and fusion between vesicles (v-SNAREs) and their target membranes (t-SNAREs). In yeast, retrograde transport from the Golgi complex to the ER is mediated by the ER t-SNARE Ufe1p, and also requires two other ER proteins, Sec20p and Tip20p, which bind each other. Although Sec20p is not a typical SNARE, we show that both it and Tip20p can be co-precipitated with Ufe1p, and that a growth-inhibiting mutation in Ufe1p can be compensated by a mutation in Sec20p. Furthermore, Sec22p, a v-SNARE implicated in forward transport from ER to Golgi, co-precipitates with Ufe1p and Sec20p, and SEC22 acts as an allele-specific multicopy suppressor of a temperature-sensitive ufe1 mutation. These results define a new functional SNARE complex, with features distinct from the plasma membrane and cis-Golgi complexes previously identified. They also show that a single v-SNARE can be involved in both anterograde and retrograde transport, which suggests that the mere presence of a particular v-SNARE may not be sufficient to determine the preferred target for a transport vesicle."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/16.11.3017"xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/16.11.3017"xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/author | "Rayner J.C."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/author | "Rayner J.C."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/author | "Lewis M.J."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/author | "Lewis M.J."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/author | "Pelham H.R.B."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/author | "Pelham H.R.B."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/pages | "3017-3024"xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/pages | "3017-3024"xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/title | "A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/title | "A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum."xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/9214619 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9214619 |
| http://purl.uniprot.org/citations/9214619 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9214619 |
| http://purl.uniprot.org/citations/9214619 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9214619 |
| http://purl.uniprot.org/citations/9214619 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9214619 |