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http://purl.uniprot.org/citations/9214747http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9214747http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9214747http://www.w3.org/2000/01/rdf-schema#comment"The period (per) locus has received much attention in molecular evolution studies because it is one of the best studied "behavioral genes" and because it offers insight into the evolution of repetitive sequences. We studied most of the coding region of per in Drosophila willistoni and confirmed previously observed patterns of conservation and divergence among distantly related species. Five regions are so highly diverged that they cannot be aligned, whereas a region encompassing the PAS domain is very conserved. Structural and nucleotide polymorphism patterns in the willistoni group are not the same as those observed in previously studied species. We sequenced the region homologous to the highly polymorphic threonine-glycine repeat of D. melanogaster in multiple strains of D. willistoni, as well as in other members of willistoni group, and found an unusual amount of conservation in this region. However, the next nonconserved region downstream in the sequence is quite variable and polymorphic for the number of repeated glycines. The glycine codon usage is significantly different in this glycine repeat as compared to other parts of the gene. We were able to plot the directionality of change in the glycine repeat region onto a phylogeny and find that the addition of glycines is the general trend with the diversification of the willistoni group."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.org/dc/terms/identifier"doi:10.1093/oxfordjournals.molbev.a025814"xsd:string
http://purl.uniprot.org/citations/9214747http://purl.org/dc/terms/identifier"doi:10.1093/oxfordjournals.molbev.a025814"xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/author"Gleason J.M."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/author"Gleason J.M."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/author"Powell J.R."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/author"Powell J.R."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/name"Mol. Biol. Evol."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/name"Mol. Biol. Evol."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/pages"741-753"xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/pages"741-753"xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/title"Interspecific and intraspecific comparisons of the period locus in the Drosophila willistoni sibling species."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/title"Interspecific and intraspecific comparisons of the period locus in the Drosophila willistoni sibling species."xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/9214747http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/9214747http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9214747
http://purl.uniprot.org/citations/9214747http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9214747
http://purl.uniprot.org/citations/9214747http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9214747
http://purl.uniprot.org/citations/9214747http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9214747
http://purl.uniprot.org/uniprot/P91716http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9214747
http://purl.uniprot.org/uniprot/Q03297http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9214747