http://purl.uniprot.org/citations/9219694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9219694 | http://www.w3.org/2000/01/rdf-schema#comment | "Proteins of the Bcl-2 family are intracellular membrane-associated proteins that regulate programmed cell death (apoptosis) either positively or negatively by as yet unknown mechanisms. Bax, a pro-apoptotic member of the Bcl-2 family, was shown to form channels in lipid membranes. Bax triggered the release of liposome-encapsulated carboxyfluorescein at both neutral and acidic pH. At physiological pH, release could be blocked by Bcl-2. Bcl-2, in contrast, triggered carboxyfluorescein release at acidic pH only. In planar lipid bilayers, Bax formed pH- and voltage-dependent ion-conducting channels. Thus, the pro-apoptotic effects of Bax may be elicited through an intrinsic pore-forming activity that can be antagonized by Bcl-2."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.277.5324.370"xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Lewis S."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Sadoul R."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Bernard A."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Martinou J.C."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Maundrell K."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Martinou I."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Gambale F."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Antonsson B."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Montessuit S."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Bernasconi L."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Conti F."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Ciavatta A."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Mazzei G."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/author | "Mermod J.J."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/pages | "370-372"xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/title | "Inhibition of Bax channel-forming activity by Bcl-2."xsd:string |
http://purl.uniprot.org/citations/9219694 | http://purl.uniprot.org/core/volume | "277"xsd:string |
http://purl.uniprot.org/citations/9219694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9219694 |
http://purl.uniprot.org/citations/9219694 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9219694 |
http://purl.uniprot.org/uniprot/P10415#attribution-D8CB4774B7A8AC2910E4C45F852E600D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9219694 |