http://purl.uniprot.org/citations/9224720 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9224720 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9224720 | http://www.w3.org/2000/01/rdf-schema#comment | "During Drosophila embryogenesis, ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally. This process, dorsal closure, requires two signaling pathways: the Drosophila Jun-amino-terminal kinase (DJNK) pathway and the Dpp pathway. We have identified mutations in DJun and show that DJNK controls dorsal closure by activating DJun and inactivating the ETS repressor Aop/Yan by phosphorylation. DJun and Aop regulate dpp expression in the most dorsal row of cells. Secreted Dpp then instructs more ventrally located cells to stretch. Our results provide a causal link between the DJNK and Dpp pathways during dorsal closure. Interestingly, in vertebrates, transforming growth factor-beta and c-Jun regulate collagenase gene expression during wound healing, a process that also involves the closing of an epithelial sheath."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.11.13.1717"xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.11.13.1717"xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/author | "Hafen E."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/author | "Hafen E."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/author | "Riesgo-Escovar J.R."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/author | "Riesgo-Escovar J.R."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/pages | "1717-1727"xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/pages | "1717-1727"xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/title | "Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/title | "Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure."xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/volume | "11"xsd:string |
http://purl.uniprot.org/citations/9224720 | http://purl.uniprot.org/core/volume | "11"xsd:string |
http://purl.uniprot.org/citations/9224720 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9224720 |
http://purl.uniprot.org/citations/9224720 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9224720 |
http://purl.uniprot.org/citations/9224720 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9224720 |
http://purl.uniprot.org/citations/9224720 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9224720 |
http://purl.uniprot.org/uniprot/P92208 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9224720 |
http://purl.uniprot.org/uniprot/P07713#attribution-18F6470B920BF2A461C77D76269DF442 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9224720 |