| http://purl.uniprot.org/citations/9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9236006 | http://www.w3.org/2000/01/rdf-schema#comment | "The role of ankyrin in the formation and stabilization of the spectrin-based skeletal meshwork and of band 3 oligomers was studied by characterizing, in nb/nb mouse red cells, the effect of ankyrin deficiency on skeletal ultrastructure, band 3-skeleton associations, and band 3 oligomeric states. Despite severe ankyrin deficiency, nb/nb mouse red cell skeletal components formed a relatively uniform two-dimensional hexagonal array of junctional complexes cross-linked by spectrin tetramers. Treatment of nb/nb ghosts with the nonionic detergent C12E8 (octaethylene glycol n-dodecyl monoether) resulted in nearly complete extraction of band 3. The extracted band 3 was present exclusively as band 3 dimers. Fluorescence photobleaching recovery and polarized fluorescence depletion measurements showed increases in the laterally (33% vs 10%) and rotationally (90% vs 76%) mobile fractions of band 3 in intact nb/nb compared to control red cells. The rotational correlation time of the major fraction of band 3 molecules was 10-fold shorter in nb/nb compared to control red cells, indicating a significant relaxation of rotational constraints in nb/nb cells. These data suggest that, although ankyrin plays a major role in strengthening the attachment of the skeleton to the membrane bilayer, ankyrin is not required for the formation of a stable two-dimensional spectrin-based skeleton. The absence of band 3 tetramers in the membrane of ankyrin-deficient red cells suggests that ankyrin is required for the formation of stable band 3 tetramers."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi9704966"xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Murray J."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Liu S.C."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Yi S.J."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Barker J.E."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Palek J."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Derick L.H."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Golan D.E."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/author | "Cho M.R."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/pages | "9596-9604"xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/title | "Red cell membranes of ankyrin-deficient nb/nb mice lack band 3 tetramers but contain normal membrane skeletons."xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/9236006 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9236006 |
| http://purl.uniprot.org/citations/9236006 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9236006 |
| http://purl.uniprot.org/uniprot/#_D3Z5M4-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J1N7-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |
| http://purl.uniprot.org/uniprot/#_E9QNT8-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |
| http://purl.uniprot.org/uniprot/#_D6RJ51-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |
| http://purl.uniprot.org/uniprot/#_G3UY11-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |
| http://purl.uniprot.org/uniprot/#_B7ZW98-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |
| http://purl.uniprot.org/uniprot/#_D3YTV8-mappedCitation-9236006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9236006 |