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http://purl.uniprot.org/citations/9236196http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9236196http://www.w3.org/2000/01/rdf-schema#comment"The Bcl6 gene has been identified from the chromosomal translocation breakpoint in B cell lymphomas, and its products are expressed highly in germinal center (GC) B cells. To investigate the function of Bcl6 in lymphocytes, we have generated RAG1-deficient mice reconstituted with bone marrow cells from Bcl6-deficient mice (Bcl6(-/-)RM). Lymphogenesis in primary lymphoid tissues of Bcl6(-/-)RM is normal, and Bcl6(-/-)RM produced control levels of primary IgG1 antibodies specific to T cell-dependent antigens. However, GCs were not found in these mice. This defect was mainly due to the abnormalities of B cells. Therefore, Bcl6 is essential for the differentiation of GC B cells."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.org/dc/terms/identifier"doi:10.1084/jem.186.3.439"xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Fukuda T."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Miki T."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Koseki H."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Okada S."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Taniguchi M."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Yoshida T."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Ishibashi K."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Hirosawa S."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Okabe S."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Tokuhisa T."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Hatano M."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/author"Miyasaka N."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/name"J Exp Med"xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/pages"439-448"xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/title"Disruption of the Bcl6 gene results in an impaired germinal center formation."xsd:string
http://purl.uniprot.org/citations/9236196http://purl.uniprot.org/core/volume"186"xsd:string
http://purl.uniprot.org/citations/9236196http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9236196
http://purl.uniprot.org/citations/9236196http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9236196
http://purl.uniprot.org/uniprot/P41183#attribution-A87E6A73B93E521328739C7DE037E574http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/9236196
http://purl.uniprot.org/uniprot/#_P41183-mappedCitation-9236196http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9236196
http://purl.uniprot.org/uniprot/#_Q8CB25-mappedCitation-9236196http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9236196