| http://purl.uniprot.org/citations/9241278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9241278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9241278 | http://www.w3.org/2000/01/rdf-schema#comment | "Although disorders of iron metabolism are prevalent, iron transport remains poorly understood. To address this problem, we undertook a positional cloning strategy to identify the causative mutation in mice with microcytic anaemia (mk). Homozygous mk/mk mice have microcytic, hypochromic anaemia due to severe defects in intestinal iron absorption and erythroid iron utilization. We report the identification of a strong candidate gene for mk, and suggest that the phenotype is a consequence of a missense mutation in Nramp2 (ref. 5), a previously identified gene of unknown function. Nramp2 is homologous to Nramp1, a gene activa in host defense. If Nramp2 is mk, as the cumulative evidence suggests, our findings have broad implications for the understanding of iron transport and resistance to intracellular pathogens."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng0897-383"xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng0897-383"xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Su M.A."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Su M.A."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Fleming M.D."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Fleming M.D."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Andrews N.C."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Andrews N.C."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Beier D.R."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Beier D.R."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Foernzler D."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Foernzler D."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Dietrich W.F."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Dietrich W.F."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Trenor C.C. III"xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/author | "Trenor C.C. III"xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/name | "Nat. Genet."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/name | "Nat. Genet."xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/pages | "383-386"xsd:string |
| http://purl.uniprot.org/citations/9241278 | http://purl.uniprot.org/core/pages | "383-386"xsd:string |