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http://purl.uniprot.org/citations/9241435 | http://www.w3.org/2000/01/rdf-schema#comment | "Southern blot analysis of mouse genomic DNA reveals two EcoRI fragments which faintly hybridize to mouse Adh-1 cDNA and are not part of the Adh-1 gene. These fragments were isolated from agarose gels, cloned, and characterized. Sequence analysis of the 2.1-kb EcoRI fragment suggests that it is likely a pseudogene since it does not contain a long open reading frame. However; the 2.0-kb EcoRI fragment contains a coding sequence with a long open reading frame which corresponds to exon 6 of the mouse Adh-1 gene. Comparison of the coding sequence with other known ADHs suggests that the sequence has diverged sufficiently from any currently known class of ADH to be a possible distinct class. Further confirmation awaits analysis of currently available genomic clones. Using these sequences as probe, restriction fragment length polymorphisms were identified for each sequence between C57Bl/6J and DBA/2J inbred mouse strains. The strain distribution pattern for these allelic differences was determined among the B x D recombinant inbred strains. This analysis revealed that the 2.1-kb EcoRI sequence is located on chromosome 3 but at a distance from the Adh-1/Adh-3 complex as previously reported. However, the new polymorphism identified in the 2.0-kb EcoRI fragment enabled this sequence to be mapped at the Adh-1/Adh-3 complex."xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.org/dc/terms/identifier | "doi:10.1023/a:1022261724493"xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/author | "Felder M.R."xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/author | "Zheng Y.W."xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/name | "Biochem Genet"xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/pages | "105-117"xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/title | "Genetic mapping of a possible new alcohol dehydrogenase sequence to mouse chromosome 3 at the Adh-1/Adh-3 complex."xsd:string |
http://purl.uniprot.org/citations/9241435 | http://purl.uniprot.org/core/volume | "35"xsd:string |
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