| http://purl.uniprot.org/citations/9270587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9270587 | http://www.w3.org/2000/01/rdf-schema#comment | "Our earlier studies had suggested a possible association between the HLA-A2 allele and Alzheimer's disease (AD). In the present study we tested the hypothesis that A2 is associated with earlier AD onset. We performed two independent studies: a collaborative study with 111 patients and a confirmatory study with 96 patients. We found similar patterns of reduced age at onset as a function of A2 in both data sets. Overall, A2 was associated with a significant 3-year shift to earlier onset. The effects of A2 and epsilon 4 on age at onset appeared additive. Our results suggest A2, or a closely linked gene, modulates onset age of AD. Association with A2 would suggest an immune/inflammatory response mechanism for AD."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.org/dc/terms/identifier | "doi:10.1212/wnl.49.2.512"xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Heston L."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Miller B."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Bird T.D."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Kaye J."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Payami H."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Schellenberg G.D."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Norman D."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Small G.W."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Zareparsi S."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Katzman R."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Head M.A."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Jarvik L.F."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Matsuyama S.S."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "McManus D.Q."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/author | "Sexton G.J."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/name | "Neurology"xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/pages | "512-518"xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/title | "Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease."xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://purl.uniprot.org/core/volume | "49"xsd:string |
| http://purl.uniprot.org/citations/9270587 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9270587 |
| http://purl.uniprot.org/citations/9270587 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9270587 |