| http://purl.uniprot.org/citations/9271578 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9271578 | http://www.w3.org/2000/01/rdf-schema#comment | "The SGS1 gene of yeast encodes a DNA helicase with homology to the human WRN gene. Mutations in WRN result in Werner's syndrome, a disease with symptoms resembling premature aging. Mutation of SGS1 is shown to cause premature aging in yeast mother cells on the basis of a shortened life-span and the aging-induced phenotypes of sterility and redistribution of the Sir3 silencing protein from telomeres to the nucleolus. Further, in old sgs1 cells the nucleolus is enlarged and fragmented-changes that also occur in old wild-type cells. These findings suggest a conserved mechanism of cellular aging that may be related to nucleolar structure."xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.277.5330.1313"xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/author | "Guarente L."xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/author | "Mills K."xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/author | "Sinclair D.A."xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/pages | "1313-1316"xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/title | "Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants."xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://purl.uniprot.org/core/volume | "277"xsd:string |
| http://purl.uniprot.org/citations/9271578 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9271578 |
| http://purl.uniprot.org/citations/9271578 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9271578 |
| http://purl.uniprot.org/uniprot/#_P35187-mappedCitation-9271578 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9271578 |
| http://purl.uniprot.org/uniprot/P35187 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9271578 |