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http://purl.uniprot.org/citations/9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9291580http://www.w3.org/2000/01/rdf-schema#comment"The activity and expression of matrix metalloproteinase-9/gelatinase B (MMP-9), an enzyme implicated in the implantation process in mice, was investigated in normal and parthenogenetic blastocyst outgrowths. Conditioned media from parthenogenetic blastocysts after 4 days of culture had reduced levels of MMP-9 activity compared to conditioned medium from normal outgrowths. Levels of MMP-9 mRNA assayed by reverse transcription-polymerase chain reaction methods were also reduced in parthenogenetic blastocysts compared to normal outgrowths. Genetic mapping studies showed that Mmp9 maps to the distal end of chromosome 2 near the proximal boundary of a region affected by genomic imprinting. Both parental alleles of Mmp9, however, are expressed in 11.5-day embryos derived from interspecific crosses of Mus musculus and Mus spretus. Thus, loss of MMP-9 activity in parthenogenetic blastocysts does not appear to be due to imprinting but, rather, due to a defect of trophoblast giant cell proliferation and differentiation."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.org/dc/terms/identifier"doi:10.1002/(sici)1520-6408(1997)21:1<55::aid-dvg6>3.0.co;2-7"xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Copeland N.G."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Gilbert D.J."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Jenkins N.A."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Edwards D.R."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Hogan A."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Schultz G.A."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Leco K.J."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/author"Harvey M.B."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/name"Dev Genet"xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/pages"55-60"xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/title"Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse."xsd:string
http://purl.uniprot.org/citations/9291580http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/9291580http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9291580
http://purl.uniprot.org/citations/9291580http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9291580
http://purl.uniprot.org/uniprot/P41245#attribution-072A849C4BD706BF27064A38269466B9http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/9291580
http://purl.uniprot.org/uniprot/#_A2A5K8-mappedCitation-9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9291580
http://purl.uniprot.org/uniprot/#_A2A5L7-mappedCitation-9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9291580
http://purl.uniprot.org/uniprot/#_P41245-mappedCitation-9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9291580
http://purl.uniprot.org/uniprot/#_P27512-mappedCitation-9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9291580
http://purl.uniprot.org/uniprot/#_Q3ULF5-mappedCitation-9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9291580
http://purl.uniprot.org/uniprot/#_Q4FK28-mappedCitation-9291580http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9291580