http://purl.uniprot.org/citations/931988 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
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http://purl.uniprot.org/citations/931988 | http://www.w3.org/2000/01/rdf-schema#comment | "The conjugation of glycine to benzoates and the conjugation of L-glutamine to certain arylacetates are catalyzed by two different acyl-CoA:amino acid N-acyltransferases which can be purified separately from liver mitochondrial fractions of either rhesus monkey or man. In both species, one transferase is specific for glycine and the other for L-glutamine. The glycine enzyme utilizes either butyryl-CoA or benzoyl-CoA as acyl donors while the glutamine enzyme uses either phenylacetyl-CoA or indoleacetyl-CoA. Acyl-CoA substrates for one transferase do not serve as substrates for the other. Additional studies with the monkey liver enzymes revealed that acyl-CoA substrates for one transferase inhibit the other, that the apparent Km value is low (10(-6) to 10(-5) M range) for the preferred acyl-CoA substrate as compared to the amino acid acceptor (greater than 10(-2) M) and that both transferases have a molecular weight of approximately 24,000. Hippuric acid and either phenylacetylglutamine or indoleacetylglutamine were characterized as the products formed by the separate enzymes."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(17)33444-0"xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/author | "Mieyal J.J."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/author | "Lucas S.V."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/author | "Siddiqui U.A."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/author | "Strong J.M."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/author | "Webster L.T."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/date | "1976"xsd:gYear |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/pages | "3352-3358"xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/title | "Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man."xsd:string |
http://purl.uniprot.org/citations/931988 | http://purl.uniprot.org/core/volume | "251"xsd:string |
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