| http://purl.uniprot.org/citations/9325265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9325265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9325265 | http://www.w3.org/2000/01/rdf-schema#comment | "The matrix metalloproteinases (MMPs) are a family of zinc-containing matrix degrading endopeptidases. A subfamily of membrane type (MT) -MMPs has been described recently. We have determined the structure of the gene (Mmp14) encoding the first MT-MMP to be described, MT1-MMP (MMP-14), and mapped it to mouse chromosome 14. The mouse MMP-14 protein is encoded by ten exons. The novel C-terminal peptide domains of MMP-14 are encoded by a single large exon that also encodes the 3'-untranslated region. The structure of the exons encoding the catalytic domain and pro-domain of MMP-14 is distinct from previously described MMP genes, whereas the exons encoding the hemopexin-like domains are similar to those of most other MMP genes. Mmp14 and the gene for tissue inhibitor of metalloproteinases-2 (Timp2) show a temporally and spatially co-regulated expression during mouse development. They are co-expressed during vascular and urogenital development and during the development of osteocartilaginous and musculotendinous structures. The stringent co-expression of these two genes suggests common regulatory pathways that may have important functional implications for the activation of pro-gelatinase A in health and disease."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.272.41.25511"xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.272.41.25511"xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Fukai N."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Fukai N."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Olsen B.R."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Olsen B.R."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Beier D.R."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Beier D.R."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Apte S.S."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/author | "Apte S.S."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/pages | "25511-25517"xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/pages | "25511-25517"xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/title | "The matrix metalloproteinase-14 (MMP-14) gene is structurally distinct from other MMP genes and is co-expressed with the TIMP-2 gene during mouse embryogenesis."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/title | "The matrix metalloproteinase-14 (MMP-14) gene is structurally distinct from other MMP genes and is co-expressed with the TIMP-2 gene during mouse embryogenesis."xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/volume | "272"xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://purl.uniprot.org/core/volume | "272"xsd:string |
| http://purl.uniprot.org/citations/9325265 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9325265 |
| http://purl.uniprot.org/citations/9325265 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9325265 |