| http://purl.uniprot.org/citations/9345306 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9345306 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9345306 | http://www.w3.org/2000/01/rdf-schema#comment | "We have cloned the cDNA containing the complete coding region of the human adrenoleukodystrophy related (ALDR) gene. The 2220-bp open reading frame encodes a 740-amino-acid polypeptide with a predicted molecular weight of 83.3 kDa. The human ALDR protein displays high similarity (62.8% identical amino acid residues) to the human adrenoleukodystrophy (ALD) gene. Analysis of ALDR expression revealed the presence of ALDR mRNA in a variety of human tissues, predominantly in brain and heart. This expression pattern is different from all other known peroxisomal ABC-transporters. Defects in the ALD gene are the primary cause of adrenoleukodystrophy, a demyelinating disorder of the central nervous system. The ALD protein (ALDP) and the ALDR gene product are peroxisomal membrane proteins belonging to the superfamily of transporters containing an ATP-binding cassette (ABC-transporters). All known peroxisomal ABC-transporters represent only one-half of a functional transporter. They are expected to form dimers either as a homodimer or as a heterodimer. ALDRP is a potential dimerization partner of ALDP or other peroxisomal ABC-transporters. The ALDR gene is a candidate for a modifier gene, accounting for the strikingly varying clinical courses of ALD observed even within a family."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.7391"xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.7391"xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Berger J."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Berger J."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Holzinger A."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Holzinger A."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Kammerer S."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Kammerer S."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Roscher A.A."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/author | "Roscher A.A."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/pages | "261-264"xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/pages | "261-264"xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/title | "cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/title | "cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter."xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/volume | "239"xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://purl.uniprot.org/core/volume | "239"xsd:string |
| http://purl.uniprot.org/citations/9345306 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9345306 |
| http://purl.uniprot.org/citations/9345306 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9345306 |