http://purl.uniprot.org/citations/9349705 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9349705 | http://www.w3.org/2000/01/rdf-schema#comment | "The HIS7 gene of Saccharomyces cerevisiae encodes a bifunctional glutamine amidotransferase: cyclase that catalyzes the formation of biosynthetic precursors for histidine and adenine. HIS7 is activated by Gcn4p upon amino acid starvation and by the Bas1/2p complex in response to adenine limitation. Mutation analysis of the HIS7 promoter in a deltagcn4 background revealed a polyd(A/T) stretch and a d(CT) repeat as essential elements for Gcn4p-independent basal HIS7 transcription. The protein binding this element was enriched and identified as the multifunctional DNA-binding protein Abf1p. Abf1p binds specifically to the d(CT) repeat sequence, which represents a novel Abf1p-binding motif, and protects 17 nucleotides from digestion by DNase I. In addition, Abf1p binding causes bending of the HIS7 promoter structure."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.org/dc/terms/identifier | "doi:10.1007/s004380050555"xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/author | "Braus G.H."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/author | "Krappmann S."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/author | "Kunzler M."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/author | "Zmasek C."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/author | "Springer C."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/name | "Mol Gen Genet"xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/pages | "136-146"xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/title | "Regulation of the yeast HIS7 gene by the global transcription factor Abf1p."xsd:string |
http://purl.uniprot.org/citations/9349705 | http://purl.uniprot.org/core/volume | "256"xsd:string |
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http://purl.uniprot.org/uniprot/P07269 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9349705 |