| http://purl.uniprot.org/citations/9364914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9364914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9364914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/9364914 | http://www.w3.org/2000/01/rdf-schema#comment | "A transposon (Tn 10dCam) insertion mutant of Escherichia coli K-12 was isolated that exhibited hypersensitivity to zinc(II) and cadmium(II) and, to a lesser extent, cobalt(II) and nickel (II). The mutated gene, located between 75.5 and 76.2 min on the chromosome, is named zntA (for Zn(II) transport or tolerance). The metal-sensitive phenotype was complemented by a genomic DNA clone mapping at 3677.90-3684.60 kb on the physical map. Insertion of a kanamycin resistance (KnR) cassette at a SalI site in a subcloned fragment generated a plasmid that partially complemented the zinc(II)-sensitive phenotype. DNA sequence analysis revealed that the KnR cassette was located within the putative promoter region of an ORF (o732 or yhhO) predicted to encode a protein of 732 amino acids, similar to cation transport P-type ATPases in the Cpx-type family. Inverse PCR and sequence analysis revealed that the Tn 10dCam element was located within o732 in the genome of the zinc(II)-sensitive mutant. The zntA mutant had elevated amounts of intracellular and cell surface-bound Zn(II), consistent with the view that zntA+ encodes a zinc(II) efflux protein. Exposure of the zntA mutant to cobalt(II) and cadmium(II) also resulted in elevated levels of intracellular and cell surface-bound metal ions."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.1997.mmi518.x"xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.1997.mmi518.x"xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Poole R.K."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Poole R.K."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Beard S.J."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Beard S.J."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Membrillo-Hernandez J."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Membrillo-Hernandez J."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Hughes M.N."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Hughes M.N."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Hashim R."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/author | "Hashim R."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/pages | "883-891"xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/pages | "883-891"xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/title | "Zinc(II) tolerance in Escherichia coli K-12: evidence that the zntA gene (o732) encodes a cation transport ATPase."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/title | "Zinc(II) tolerance in Escherichia coli K-12: evidence that the zntA gene (o732) encodes a cation transport ATPase."xsd:string |
| http://purl.uniprot.org/citations/9364914 | http://purl.uniprot.org/core/volume | "25"xsd:string |